In 2025, two drugs earned more than double the combined revenue of OpenAI and Anthropic and reached under 2% of the people who qualify. This is a deep dive on the biology, the economics, and where...
Deep Dive: What Happens When Cars Drive Themselves
Autonomous driving reached commercial scale in 2025. The robotaxi market alone is valued at over $11 trillion. But the bigger story is what happens to the industries built around human drivers...
Cyberwarfare lets a small number of operators threaten systems that took decades and billions to build. The next question is how that balance changes when AI can run most of an attack at...
SpaceX lowered the cost of reaching orbit by 20x, then used that advantage to build Starlink. The next question is whether the same route can unlock something even larger: broadband, AI compute, & ...
Cancer, heart disease, dementia, and type 2 diabetes are funded, researched, and treated as separate problems. However, they share one underlying driver...
The 60-year-old code behind $5 trillion in healthcare
The U.S. spends $5.3T a year on healthcare, yet patient medical records are often fragmented across more than 10 disconnected systems. Its core architecture has...
Deep Dive: The Frontier of Physical AI with Humanoid Robotics
Viral videos of humanoids dances and backflips have sparked interest in the sector. Despite early excitement, the question remains: when is it reasonable to expect...
Deep Dive on Neuralink: Controlling Computers With Your Mind
Neuralink is pursuing one of the most difficult frontiers in technology. The implications include reversing neurological disabilities, modulating circuits involved in...
In 2025, the energy landscape hit a historic inflection point. Solar now attracts ~$500B in investments each year, more capital than all other electricity sources combined. What happened?
The perception of quantum computing has oscillated between two extremes: it is either treated as distant science fiction or marketed as an all-purpose supercomputer posing an imminent threat to...
Deep Dive: The Electric Grid - America’s Biggest Bottleneck of the Decade
From 1900 to 2000, new grid power capacity increased 10x every 30 years. In the last 25 years, it has only grown 1.3x. The U.S. electric grid is rated by engineers at a D+ and now stands as our...
Microsoft has spent fifty years building platforms that sit underneath the modern economy. BASIC made early computers usable. MS DOS and Windows standardized personal computing. Office and Azure be...
What drives the Mag7's revenues and bottom lines? How do they allocate capital, and are they positioned for continued outsized returns? How should we understand them in relation to the market overall?
What drives the Mag7's revenues and bottom lines? How do they allocate capital, and are they positioned for continued outsized returns? How should we understand them in relation to the market overall?
What drives the Mag7's revenues and bottom lines? How do they allocate capital, and are they positioned for continued outsized returns? How should we understand them in relation to the market overall?
What drives the Mag7's revenues and bottom lines? How do they allocate capital, and are they positioned for continued outsized returns? How should we understand them in relation to the market overall?
What are the use cases for stablecoins, and how have they achieved product-market fit? What are the implications for U.S. markets? How will U.S. regulatory clarity impact the stablecoin ecosystem?
How is Groq positioning itself in response to NVIDIA's dominance? What companies are running profitable AI inference workloads today? How are geopolitics shaping the AI compute infrastructure?
How do we navigate an ever-evolving media landscape? How have algorithmic systems disrupted the traditional media ecosystem? Who are the new sense-makers and is there a new creator playbook forming?
What are cryptocurrencies and how do they work? What are some notable cryptocurrencies in the ecosystem today? Which aspects of the crypto ecosystem create value?
How do drugs interact with biological processes in the body? How does drug development work? Why have companies developing novel drugs seen poor returns over the past decade?